BREKIYA (AUTOINJECTOR) vs DIHYDROERGOTAMINE MESYLATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Attribute	BREKIYA (AUTOINJECTOR)	DIHYDROERGOTAMINE MESYLATE
Rating	70/100	New
Pharmacy pays	$34.84 /mL	$34.84 /mL
Type	RX	RX
Active ingredient	DIHYDROERGOTAMINE MESYLATE	DIHYDROERGOTAMINE MESYLATE
Manufacturer	Amneal	Somerset Theraps LLC
Dosage forms	Injectable	Injectable, Solution, Spray/Inhaler, Spray/Inhaler, metered
Drug class	Ergotamine Derivative	Ergotamine Derivative
Boxed warning	Boxed warning	Boxed warning
Half-life	about 9 to 13 hours, depending on the form	about 9 to 13 hours, depending on the form
Treats	Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension	Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension

brekiya (autoinjector)dihydroergotamine mesylate

Rating

70/100

New

Pharmacy pays

$34.84 /mL

Type

Active ingredient

DIHYDROERGOTAMINE MESYLATE

Manufacturer

Amneal

Somerset Theraps LLC

Dosage forms

Injectable

Injectable, Solution, Spray/Inhaler, Spray/Inhaler, metered

Drug class

Ergotamine Derivative

Boxed warning

Half-life

about 9 to 13 hours, depending on the form

Treats

Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension

Frequently asked questions

Which is cheaper, Brekiya (Autoinjector) or Dihydroergotamine Mesylate?

Pharmacies pay about the same to acquire either one — roughly $34.84 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Brekiya (Autoinjector) and Dihydroergotamine Mesylate?

Both Brekiya (Autoinjector) and Dihydroergotamine Mesylate share the active ingredient Dihydroergotamine Mesylate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.