BOSENTAN vs LETAIRIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. BOSENTAN and LETAIRIS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BOSENTAN	LETAIRIS
Rating	66/100	70/100
Pharmacy pays	—	~$255.61 /30
Type	RX	RX
Active ingredient	BOSENTAN	AMBRISENTAN
Manufacturer	Zydus Pharms USA Inc	Gilead Sciences Inc
Dosage forms	Tablet	Tablet
Drug class	Endothelin Receptor Antagonist	Endothelin Receptor Antagonist
Boxed warning	Boxed warning	Boxed warning
Treats	Pulmonary Hypertension	Pulmonary Hypertension

bosentan letairis

Rating

66/100

70/100

Pharmacy pays

—

~$255.61 /30

Type

Active ingredient

BOSENTAN

AMBRISENTAN

Manufacturer

Zydus Pharms USA Inc

Gilead Sciences Inc

Dosage forms

Tablet

Drug class

Endothelin Receptor Antagonist

Boxed warning

Treats

Pulmonary Hypertension

Frequently asked questions

Which is better-rated, Bosentan or Letairis?

By our independent rating, Letairis scores higher — 3.5 vs 3.3 out of 5 for Bosentan. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Bosentan and Letairis?

Bosentan contains Bosentan, while Letairis contains Ambrisentan — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.