BICILLIN L-A vs POLYCILLIN-N

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. BICILLIN L-A and POLYCILLIN-N are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BICILLIN L-A	POLYCILLIN-N
Rating	New	New
Pharmacy pays	—	~$13.42 /30
Type	RX	RX
Active ingredient	PENICILLIN G BENZATHINE	AMPICILLIN SODIUM
Manufacturer	Wyeth Ayerst	Bristol
Dosage forms	Injectable	Injectable
Drug class	Penicillin-Class Antibacterial	Penicillin-Class Antibacterial
Boxed warning	None	None
Treats	Actinomycosis, Anthrax, Botulism	Actinomycosis, Human Bites, Bacillary Dysentery

bicillin l-a polycillin-n

Rating

New

Pharmacy pays

—

~$13.42 /30

Type

Active ingredient

PENICILLIN G BENZATHINE

AMPICILLIN SODIUM

Manufacturer

Wyeth Ayerst

Bristol

Dosage forms

Injectable

Drug class

Penicillin-Class Antibacterial

Boxed warning

None

Treats

Actinomycosis, Anthrax, Botulism

Actinomycosis, Human Bites, Bacillary Dysentery

Frequently asked questions

What is the difference between Bicillin L-A and Polycillin-N?

Bicillin L-A contains Penicillin G Benzathine, while Polycillin-N contains Ampicillin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.