BIAXIN XL vs ZMAX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. BIAXIN XL and ZMAX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BIAXIN XL	ZMAX
Rating	72/100	New
Pharmacy pays	$0.47 /mL	~$9.48 /30
Type	RX	RX
Active ingredient	CLARITHROMYCIN	AZITHROMYCIN
Manufacturer	Abbvie	Pf Prism Cv
Dosage forms	Tablet, Tablet, extended release	—
Drug class	Macrolide Antimicrobial	Macrolide Antimicrobial
Boxed warning	None	None
Half-life	about 3 to 4 hours at 250 mg, rising to 5 to 7 hours at 500 mg (dose-dependent)	about 68 hours
Treats	Bronchitis, Chlamydia Infections, Duodenal Ulcer	Chlamydia Infections, Haemophilus Infections, Nontuberculous Mycobacterium Infections

biaxin xl zmax

Rating

72/100

New

Pharmacy pays

$0.47 /mL

~$9.48 /30

Type

Active ingredient

CLARITHROMYCIN

AZITHROMYCIN

Manufacturer

Abbvie

Pf Prism Cv

Dosage forms

Tablet, Tablet, extended release

—

Drug class

Macrolide Antimicrobial

Boxed warning

None

Half-life

about 3 to 4 hours at 250 mg, rising to 5 to 7 hours at 500 mg (dose-dependent)

about 68 hours

Treats

Bronchitis, Chlamydia Infections, Duodenal Ulcer

Chlamydia Infections, Haemophilus Infections, Nontuberculous Mycobacterium Infections

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Frequently asked questions

What is the difference between Biaxin XL and Zmax?

Biaxin XL contains Clarithromycin, while Zmax contains Azithromycin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.