BETAPACE AF vs NEXTERONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. BETAPACE AF and NEXTERONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BETAPACE AF	NEXTERONE
Rating	New	New
Pharmacy pays	~$2.96 /30	~$3.68 /30
Type	RX	RX
Active ingredient	SOTALOL HYDROCHLORIDE	AMIODARONE HYDROCHLORIDE
Manufacturer	Legacy Pharma	Baxter Hlthcare
Dosage forms	Tablet	Injectable
Drug class	Antiarrhythmic	Antiarrhythmic
Boxed warning	Boxed warning	None
Half-life	about 12 hours (the label gives a mean elimination half-life of 12 hours)	—
Treats	Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia	Supraventricular Tachycardia, Ventricular Fibrillation

betapace af nexterone

Rating

New

Pharmacy pays

~$2.96 /30

~$3.68 /30

Type

Active ingredient

SOTALOL HYDROCHLORIDE

AMIODARONE HYDROCHLORIDE

Manufacturer

Legacy Pharma

Baxter Hlthcare

Dosage forms

Tablet

Injectable

Drug class

Antiarrhythmic

Boxed warning

None

Half-life

about 12 hours (the label gives a mean elimination half-life of 12 hours)

—

Treats

Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia

Supraventricular Tachycardia, Ventricular Fibrillation

Frequently asked questions

Which is cheaper, Betapace Af or Nexterone?

Betapace Af costs pharmacies less to acquire — about $2.96 vs $3.68 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Betapace Af and Nexterone?

Betapace Af contains Sotalol Hydrochloride, while Nexterone contains Amiodarone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.