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BENZAMYCIN vs POLYSPORIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. BENZAMYCIN and POLYSPORIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

74/100
72/100

Pharmacy pays

$0.05 /g
—

Type

RX
RX

Active ingredient

BENZOYL PEROXIDE AND ERYTHROMYCIN
BACITRACIN ZINC AND POLYMYXIN B SULFATE

Dosage forms

Kit
Spray/Inhaler, Topical

Drug class

—
—

Boxed warning

None
None

Frequently asked questions

Which is better-rated, Benzamycin or Polysporin?

By our independent rating, Benzamycin scores higher — 3.7 vs 3.6 out of 5 for Polysporin. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Benzamycin and Polysporin?

Benzamycin contains Benzoyl Peroxide and Erythromycin, while Polysporin contains Bacitracin Zinc and Polymyxin B Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.