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BENYLIN vs PATANASE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. BENYLIN and PATANASE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$0.04 /mL
$1.23 /g

Type

RX
RX

Active ingredient

DIPHENHYDRAMINE HYDROCHLORIDE
OLOPATADINE HYDROCHLORIDE

Dosage forms

Syrup, Solution
Spray/Inhaler, metered

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Treats

Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness
Allergic Conjunctivitis

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Frequently asked questions

What is the difference between Benylin and Patanase?

Benylin contains Diphenhydramine Hydrochloride, while Patanase contains Olopatadine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.