BENYLIN vs PATADAY ONCE DAILY RELIEF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	BENYLIN	PATADAY ONCE DAILY RELIEF
Rating	New	New
Pharmacy pays	$0.04 /mL	$1.23 /g
Type	RX	OTC
Active ingredient	DIPHENHYDRAMINE HYDROCHLORIDE	OLOPATADINE HYDROCHLORIDE
Manufacturer	Parke Davis	Alcon
Dosage forms	Syrup, Solution	Solution
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Treats	Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness	Allergic Conjunctivitis

benylin pataday once daily relief

Rating

New

Pharmacy pays

$0.04 /mL

$1.23 /g

Type

OTC

Active ingredient

DIPHENHYDRAMINE HYDROCHLORIDE

OLOPATADINE HYDROCHLORIDE

Manufacturer

Parke Davis

Alcon

Dosage forms

Syrup, Solution

Solution

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Treats

Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness

Allergic Conjunctivitis

Get benylinhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

What is the difference between Benylin and Pataday Once Daily Relief?

Benylin contains Diphenhydramine Hydrochloride, while Pataday Once Daily Relief contains Olopatadine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.