BENYLIN vs CLARINEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. BENYLIN and CLARINEX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BENYLIN	CLARINEX
Rating	New	New
Pharmacy pays	$0.04 /mL	~$8.60 /30
Type	RX	RX
Active ingredient	DIPHENHYDRAMINE HYDROCHLORIDE	DESLORATADINE
Manufacturer	Parke Davis	Schering
Dosage forms	Syrup, Solution	Tablet
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Treats	Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness	Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

benylin clarinex

Rating

New

Pharmacy pays

$0.04 /mL

~$8.60 /30

Type

Active ingredient

DIPHENHYDRAMINE HYDROCHLORIDE

DESLORATADINE

Manufacturer

Parke Davis

Schering

Dosage forms

Syrup, Solution

Tablet

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Treats

Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness

Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Benylin and Clarinex?

Benylin contains Diphenhydramine Hydrochloride, while Clarinex contains Desloratadine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.