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BELBUCA vs BUPRENEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$683.94 /30
~$683.94 /30

Type

RX
RX

Active ingredient

BUPRENORPHINE HYDROCHLORIDE
BUPRENORPHINE HYDROCHLORIDE

Manufacturer

Dosage forms

Film, Soluble
Injectable

Drug class

Partial Opioid Agonist
Partial Opioid Agonist

Boxed warning

Treats

Heroin Dependence, Pain
Heroin Dependence, Pain

Frequently asked questions

Which is cheaper, Belbuca or Buprenex?

Pharmacies pay about the same to acquire either one — roughly $683.94 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Belbuca and Buprenex?

Both Belbuca and Buprenex share the active ingredient Buprenorphine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.