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BACTRIM DS vs SULFAMETHOXAZOLE AND TRIMETHOPRIM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

64/100
72/100

Pharmacy pays

Type

RX
RX

Active ingredient

SULFAMETHOXAZOLE AND TRIMETHOPRIM
SULFAMETHOXAZOLE AND TRIMETHOPRIM

Dosage forms

Tablet
Injectable, Suspension, Tablet

Drug class

Boxed warning

None
None

Half-life

about 10 hours
about 10 hours

Frequently asked questions

Which is better-rated, Bactrim Ds or Sulfamethoxazole and Trimethoprim?

By our independent rating, Sulfamethoxazole and Trimethoprim scores higher — 3.6 vs 3.2 out of 5 for Bactrim Ds. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Bactrim Ds and Sulfamethoxazole and Trimethoprim?

Both Bactrim Ds and Sulfamethoxazole and Trimethoprim share the active ingredient Sulfamethoxazole and Trimethoprim.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.