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AZILECT vs EMSAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. AZILECT and EMSAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

56/100
New

Pharmacy pays

~$30.35 /30
~$19.56 /30

Type

RX
RX

Active ingredient

RASAGILINE MESYLATE
SELEGILINE

Manufacturer

Dosage forms

Tablet
Patch

Drug class

Monoamine Oxidase Inhibitor
Monoamine Oxidase Inhibitor

Boxed warning

None
None

Treats

Parkinson Disease
Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

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Frequently asked questions

Which is cheaper, Azilect or Emsam?

Emsam costs pharmacies less to acquire — about $19.56 vs $30.35 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Azilect and Emsam?

Azilect contains Rasagiline Mesylate, while Emsam contains Selegiline — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.