AZILECT vs COMTAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. AZILECT and COMTAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AZILECT	COMTAN
Rating	56/100	New
Pharmacy pays	~$30.21 /30	~$10.59 /30
Type	RX	RX
Active ingredient	RASAGILINE MESYLATE	ENTACAPONE
Manufacturer	Teva	Orion Pharma
Dosage forms	Tablet	Tablet
Drug class	Monoamine Oxidase Inhibitor	Catechol-O-Methyltransferase Inhibitor
Boxed warning	None	None
Treats	Parkinson Disease	Parkinson Disease

azilect comtan

Rating

56/100

New

Pharmacy pays

~$30.21 /30

~$10.59 /30

Type

Active ingredient

RASAGILINE MESYLATE

ENTACAPONE

Manufacturer

Teva

Orion Pharma

Dosage forms

Tablet

Drug class

Monoamine Oxidase Inhibitor

Catechol-O-Methyltransferase Inhibitor

Boxed warning

None

Treats

Parkinson Disease

Frequently asked questions

Which is cheaper, Azilect or Comtan?

Comtan costs pharmacies less to acquire — about $10.59 vs $30.21 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Azilect and Comtan?

Azilect contains Rasagiline Mesylate, while Comtan contains Entacapone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.