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AZELASTINE HYDROCHLORIDE vs CETIRIZINE HYDROCHLORIDE HIVES

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

$0.58 /mL
$0.06 /mL

Type

RX
OTC

Active ingredient

AZELASTINE HYDROCHLORIDE
CETIRIZINE HYDROCHLORIDE

Dosage forms

Drops, Spray/Inhaler, metered
Tablet

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Half-life

about 8.3 hours (mean in healthy adults)

Treats

Allergic Conjunctivitis, Perennial Allergic Rhinitis, Vasomotor Rhinitis
Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

Which is cheaper, Azelastine Hydrochloride or Cetirizine Hydrochloride Hives?

Cetirizine Hydrochloride Hives costs pharmacies less to acquire — about $0.06 vs $0.58 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Azelastine Hydrochloride and Cetirizine Hydrochloride Hives?

Azelastine Hydrochloride contains Azelastine Hydrochloride, while Cetirizine Hydrochloride Hives contains Cetirizine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.