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AZASITE vs ZAGAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. AZASITE and ZAGAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
64/100

Pharmacy pays

~$9.39 /30
—

Type

RX
RX

Active ingredient

AZITHROMYCIN
SPARFLOXACIN

Manufacturer

Dosage forms

Drops
Tablet

Drug class

Macrolide Antimicrobial
—

Boxed warning

None
None

Half-life

about 68 hours
—

Treats

Chlamydia Infections, Haemophilus Infections, Nontuberculous Mycobacterium Infections
Chlamydia Infections, Escherichia Coli Infections, Haemophilus Infections

Frequently asked questions

Which is better-rated, Azasite or Zagam?

By our independent rating, Azasite scores higher — 3.6 vs 3.2 out of 5 for Zagam. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Azasite and Zagam?

Azasite contains Azithromycin, while Zagam contains Sparfloxacin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.