AZASITE vs BIAXIN XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. AZASITE and BIAXIN XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AZASITE	BIAXIN XL
Rating	70/100	72/100
Pharmacy pays	~$9.48 /30	$0.47 /mL
Type	RX	RX
Active ingredient	AZITHROMYCIN	CLARITHROMYCIN
Manufacturer	Thea Pharma	Abbvie
Dosage forms	Drops	Tablet, Tablet, extended release
Drug class	Macrolide Antimicrobial	Macrolide Antimicrobial
Boxed warning	None	None
Half-life	about 68 hours	about 3 to 4 hours at 250 mg, rising to 5 to 7 hours at 500 mg (dose-dependent)
Treats	Chlamydia Infections, Haemophilus Infections, Nontuberculous Mycobacterium Infections	Bronchitis, Chlamydia Infections, Duodenal Ulcer

azasite biaxin xl

Rating

70/100

72/100

Pharmacy pays

~$9.48 /30

$0.47 /mL

Type

Active ingredient

AZITHROMYCIN

CLARITHROMYCIN

Manufacturer

Thea Pharma

Abbvie

Dosage forms

Drops

Tablet, Tablet, extended release

Drug class

Macrolide Antimicrobial

Boxed warning

None

Half-life

about 68 hours

about 3 to 4 hours at 250 mg, rising to 5 to 7 hours at 500 mg (dose-dependent)

Treats

Chlamydia Infections, Haemophilus Infections, Nontuberculous Mycobacterium Infections

Bronchitis, Chlamydia Infections, Duodenal Ulcer

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Frequently asked questions

Which is better-rated, Azasite or Biaxin XL?

By our independent rating, Biaxin XL scores higher — 3.6 vs 3.5 out of 5 for Azasite. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Azasite and Biaxin XL?

Azasite contains Azithromycin, while Biaxin XL contains Clarithromycin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.