AYVAKIT vs TEPMETKO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. AYVAKIT and TEPMETKO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AYVAKIT	TEPMETKO
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	AVAPRITINIB	TEPOTINIB HYDROCHLORIDE
Manufacturer	Blueprint Medicines	Emd Serono
Dosage forms	Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Gastrointestinal Stromal Tumors	—

ayvakit tepmetko

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

AVAPRITINIB

TEPOTINIB HYDROCHLORIDE

Manufacturer

Blueprint Medicines

Emd Serono

Dosage forms

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Gastrointestinal Stromal Tumors

—

Frequently asked questions

What is the difference between Ayvakit and Tepmetko?

Ayvakit contains Avapritinib, while Tepmetko contains Tepotinib Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.