AYVAKIT vs OFEV

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. AYVAKIT and OFEV are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AYVAKIT	OFEV
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	AVAPRITINIB	NINTEDANIB ESYLATE
Manufacturer	Blueprint Medicines	Boehringer Ingelheim
Dosage forms	Tablet	Capsule
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Gastrointestinal Stromal Tumors	Idiopathic Pulmonary Fibrosis

ayvakit ofev

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

AVAPRITINIB

NINTEDANIB ESYLATE

Manufacturer

Blueprint Medicines

Boehringer Ingelheim

Dosage forms

Tablet

Capsule

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Gastrointestinal Stromal Tumors

Idiopathic Pulmonary Fibrosis

Frequently asked questions

What is the difference between Ayvakit and Ofev?

Ayvakit contains Avapritinib, while Ofev contains Nintedanib Esylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.