AYVAKIT vs NEXAVAR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. AYVAKIT and NEXAVAR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AYVAKIT	NEXAVAR
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	AVAPRITINIB	SORAFENIB TOSYLATE
Manufacturer	Blueprint Medicines	Bayer Hlthcare
Dosage forms	Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Gastrointestinal Stromal Tumors	Renal Cell Carcinoma, Hepatocellular Carcinoma, Thyroid Neoplasms

ayvakit nexavar

Rating

New

Pharmacy pays

—

Type

Active ingredient

AVAPRITINIB

SORAFENIB TOSYLATE

Manufacturer

Blueprint Medicines

Bayer Hlthcare

Dosage forms

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Gastrointestinal Stromal Tumors

Renal Cell Carcinoma, Hepatocellular Carcinoma, Thyroid Neoplasms

Frequently asked questions

What is the difference between Ayvakit and Nexavar?

Ayvakit contains Avapritinib, while Nexavar contains Sorafenib Tosylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.