Skip to content
ppharmaranks
Menu

AYGESTIN vs MEGESTROL ACETATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. AYGESTIN and MEGESTROL ACETATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

~$2.83 /30
~$7.14 /30

Type

RX
RX

Active ingredient

NORETHINDRONE ACETATE
MEGESTROL ACETATE

Dosage forms

Tablet
Tablet, Suspension

Drug class

Progestin
Progestin

Boxed warning

None
None

Half-life

about 8 hours

Treats

Acne Vulgaris, Endometrial Hyperplasia, Endometriosis
Anorexia, Breast Neoplasms, Cachexia

Get aygestin

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

Frequently asked questions

Which is cheaper, Aygestin or Megestrol Acetate?

Aygestin costs pharmacies less to acquire — about $2.83 vs $7.14 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Aygestin and Megestrol Acetate?

Aygestin contains Norethindrone Acetate, while Megestrol Acetate contains Megestrol Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.