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AYGESTIN vs DEPO-SUBQ PROVERA 104

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. AYGESTIN and DEPO-SUBQ PROVERA 104 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
64/100

Pharmacy pays

~$2.83 /30
~$562.79 /30

Type

RX
RX

Active ingredient

NORETHINDRONE ACETATE
MEDROXYPROGESTERONE ACETATE

Manufacturer

Dosage forms

Tablet
Injectable

Drug class

Progestin
Progestin

Boxed warning

Half-life

about 8 hours

Treats

Acne Vulgaris, Endometrial Hyperplasia, Endometriosis
Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

Get aygestin

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Frequently asked questions

Which is cheaper, Aygestin or Depo-Subq Provera 104?

Aygestin costs pharmacies less to acquire — about $2.83 vs $562.79 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Aygestin and Depo-Subq Provera 104?

Aygestin contains Norethindrone Acetate, while Depo-Subq Provera 104 contains Medroxyprogesterone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.