AXTLE vs GILOTRIF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. AXTLE and GILOTRIF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AXTLE	GILOTRIF
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PEMETREXED DIPOTASSIUM	AFATINIB DIMALEATE
Manufacturer	Avyxa Holdings	Boehringer Ingelheim
Dosage forms	Injectable	Tablet
Drug class	—	—
Boxed warning	None	None
Treats	Malignant Mesothelioma, Non-Small-Cell Lung Carcinoma, Lung Neoplasms	Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

axtle gilotrif

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

PEMETREXED DIPOTASSIUM

AFATINIB DIMALEATE

Manufacturer

Avyxa Holdings

Boehringer Ingelheim

Dosage forms

Injectable

Tablet

Drug class

—

Boxed warning

None

Treats

Malignant Mesothelioma, Non-Small-Cell Lung Carcinoma, Lung Neoplasms

Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

Frequently asked questions

What is the difference between Axtle and Gilotrif?

Axtle contains Pemetrexed Dipotassium, while Gilotrif contains Afatinib Dimaleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.