AVENTYL HYDROCHLORIDE vs ZONALON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. AVENTYL HYDROCHLORIDE and ZONALON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AVENTYL HYDROCHLORIDE	ZONALON
Rating	New	66/100
Pharmacy pays	$0.17 /mL	~$4.84 /30
Type	RX	RX
Active ingredient	NORTRIPTYLINE HYDROCHLORIDE	DOXEPIN HYDROCHLORIDE
Manufacturer	Lilly	Mylan
Dosage forms	Capsule	Topical
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	None	None
Half-life	—	about 8 to 24 hours (average about 17 hours)
Treats	Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder	Anxiety Disorders, Depressive Disorder, Atopic Dermatitis

aventyl hydrochloride zonalon

Rating

New

66/100

Pharmacy pays

$0.17 /mL

~$4.84 /30

Type

Active ingredient

NORTRIPTYLINE HYDROCHLORIDE

DOXEPIN HYDROCHLORIDE

Manufacturer

Lilly

Mylan

Dosage forms

Capsule

Topical

Drug class

Tricyclic Antidepressant

Boxed warning

None

Half-life

—

about 8 to 24 hours (average about 17 hours)

Treats

Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

Anxiety Disorders, Depressive Disorder, Atopic Dermatitis

Get zonalonhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

What is the difference between Aventyl Hydrochloride and Zonalon?

Aventyl Hydrochloride contains Nortriptyline Hydrochloride, while Zonalon contains Doxepin Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.