AVANDAMET vs COLAZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. AVANDAMET and COLAZAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AVANDAMET	COLAZAL
Rating	New	74/100
Pharmacy pays	~$0.74 /30	~$11.02 /30
Type	RX	RX
Active ingredient	METFORMIN HYDROCHLORIDE AND ROSIGLITAZONE MALEATE	BALSALAZIDE DISODIUM
Manufacturer	Sb Pharmco	Valeant Pharm Intl
Dosage forms	Tablet	Capsule
Drug class	—	Aminosalicylate
Boxed warning	None	None
Half-life	about 6.2 hours (plasma elimination half-life in adults with normal kidney function)	—
Treats	—	Ulcerative Colitis

avandamet colazal

Rating

New

74/100

Pharmacy pays

~$0.74 /30

~$11.02 /30

Type

Active ingredient

METFORMIN HYDROCHLORIDE AND ROSIGLITAZONE MALEATE

BALSALAZIDE DISODIUM

Manufacturer

Sb Pharmco

Valeant Pharm Intl

Dosage forms

Tablet

Capsule

Drug class

—

Aminosalicylate

Boxed warning

None

Half-life

about 6.2 hours (plasma elimination half-life in adults with normal kidney function)

—

Treats

—

Ulcerative Colitis

Frequently asked questions

Which is cheaper, Avandamet or Colazal?

Avandamet costs pharmacies less to acquire — about $0.74 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Avandamet and Colazal?

Avandamet contains Metformin Hydrochloride and Rosiglitazone Maleate, while Colazal contains Balsalazide Disodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.