AUGMENTIN ES-600 vs AUGMENTIN XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 30, 2026·How we rate

Attribute	AUGMENTIN ES-600	AUGMENTIN XR
Rating	New	New
Pharmacy pays	$0.04 /mL	$0.04 /mL
Type	RX	RX
Active ingredient	AMOXICILLIN AND CLAVULANATE POTASSIUM	AMOXICILLIN AND CLAVULANATE POTASSIUM
Manufacturer	US Antibiotics	US Antibiotics
Dosage forms	—	Tablet, extended release
Drug class	—	—
Boxed warning	None	None
Half-life	about 1 hour (roughly 61 minutes)	about 1 hour (roughly 61 minutes)

augmentin es-600 augmentin xr

Rating

New

Pharmacy pays

$0.04 /mL

Type

Active ingredient

AMOXICILLIN AND CLAVULANATE POTASSIUM

Manufacturer

US Antibiotics

Dosage forms

—

Tablet, extended release

Drug class

—

Boxed warning

None

Half-life

about 1 hour (roughly 61 minutes)

Frequently asked questions

Which is cheaper, Augmentin Es-600 or Augmentin XR?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Augmentin Es-600 and Augmentin XR?

Both Augmentin Es-600 and Augmentin XR share the active ingredient Amoxicillin and Clavulanate Potassium.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.