AUGMENTIN '250' vs AUGMENTIN XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	AUGMENTIN '250'	AUGMENTIN XR
Rating	New	New
Pharmacy pays	$0.04 /mL	$0.04 /mL
Type	RX	RX
Active ingredient	AMOXICILLIN AND CLAVULANATE POTASSIUM	AMOXICILLIN AND CLAVULANATE POTASSIUM
Manufacturer	US Antibiotics	US Antibiotics
Dosage forms	Tablet, chewable, Tablet	Tablet, extended release
Drug class	—	—
Boxed warning	None	None
Half-life	about 1 hour (roughly 61 minutes)	about 1 hour (roughly 61 minutes)

augmentin '250'augmentin xr

Rating

New

Pharmacy pays

$0.04 /mL

Type

Active ingredient

AMOXICILLIN AND CLAVULANATE POTASSIUM

Manufacturer

US Antibiotics

Dosage forms

Tablet, chewable, Tablet

Tablet, extended release

Drug class

—

Boxed warning

None

Half-life

about 1 hour (roughly 61 minutes)

Frequently asked questions

Which is cheaper, Augmentin '250' or Augmentin XR?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Augmentin '250' and Augmentin XR?

Both Augmentin '250' and Augmentin XR share the active ingredient Amoxicillin and Clavulanate Potassium.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.