AUBAGIO vs MAYZENT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. AUBAGIO and MAYZENT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AUBAGIO	MAYZENT
Rating	70/100	70/100
Pharmacy pays	~$16.32 /30	—
Type	RX	RX
Active ingredient	TERIFLUNOMIDE	SIPONIMOD
Manufacturer	Sanofi Aventis US	Novartis
Dosage forms	Tablet	Tablet
Drug class	Pyrimidine Synthesis Inhibitor	—
Boxed warning	Boxed warning	None
Treats	Relapsing-Remitting Multiple Sclerosis	Chronic Progressive Multiple Sclerosis, Relapsing-Remitting Multiple Sclerosis

aubagio mayzent

Rating

70/100

Pharmacy pays

~$16.32 /30

—

Type

Active ingredient

TERIFLUNOMIDE

SIPONIMOD

Manufacturer

Sanofi Aventis US

Novartis

Dosage forms

Tablet

Drug class

Pyrimidine Synthesis Inhibitor

—

Boxed warning

None

Treats

Relapsing-Remitting Multiple Sclerosis

Chronic Progressive Multiple Sclerosis, Relapsing-Remitting Multiple Sclerosis

Frequently asked questions

Which is better-rated, Aubagio or Mayzent?

Aubagio and Mayzent are tied at 3.5 out of 5 by our independent rating.

What is the difference between Aubagio and Mayzent?

Aubagio contains Teriflunomide, while Mayzent contains Siponimod — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.