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ATMEKSI vs METAXALONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ATMEKSI and METAXALONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

~$1.27 /30
~$11.97 /30

Type

RX
RX

Active ingredient

METHOCARBAMOL
METAXALONE

Dosage forms

Suspension
Tablet

Drug class

Muscle Relaxant
Muscle Relaxant

Boxed warning

None
None

Half-life

about 1 to 2 hours
about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)

Treats

Muscle Cramp, Muscle Rigidity, Myositis
Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Frequently asked questions

Which is cheaper, Atmeksi or Metaxalone?

Atmeksi costs pharmacies less to acquire — about $1.27 vs $11.97 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Atmeksi and Metaxalone?

Atmeksi contains Methocarbamol, while Metaxalone contains Metaxalone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.