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ATENOLOL vs TOPROL-XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ATENOLOL and TOPROL-XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

62/100
New

Pharmacy pays

~$0.76 /30
~$0.58 /30

Type

RX
RX

Active ingredient

ATENOLOL
METOPROLOL SUCCINATE

Dosage forms

Tablet
Tablet, extended release

Drug class

Beta-Adrenergic Blocker
Beta-Adrenergic Blocker

Boxed warning

None
None

Half-life

about 6 to 7 hours
about 3 to 4 hours

Treats

Angina Pectoris, Atrial Fibrillation, Atrial Flutter
Angina Pectoris, Atrial Fibrillation, Atrial Flutter

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Frequently asked questions

Which is cheaper, Atenolol or Toprol-XL?

Toprol-XL costs pharmacies less to acquire — about $0.58 vs $0.76 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Atenolol and Toprol-XL?

Atenolol contains Atenolol, while Toprol-XL contains Metoprolol Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.