ATARAX vs DECAPRYN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 14, 2026·How we rate

Possible drug interaction. ATARAX and DECAPRYN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ATARAX	DECAPRYN
Rating	64/100	70/100
Pharmacy pays	$0.04 /mL	—
Type	RX	RX
Active ingredient	HYDROXYZINE HYDROCHLORIDE	DOXYLAMINE SUCCINATE
Manufacturer	Pfizer	Sanofi Aventis US
Dosage forms	Tablet	Tablet
Drug class	Antihistamine	Antihistamine
Boxed warning	None	None
Half-life	about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours)	—
Treats	Anxiety Disorders, Nausea, Pruritus	Headache, Sleep Initiation and Maintenance Disorders, Perennial Allergic Rhinitis

atarax decapryn

Rating

64/100

70/100

Pharmacy pays

$0.04 /mL

—

Type

Active ingredient

HYDROXYZINE HYDROCHLORIDE

DOXYLAMINE SUCCINATE

Manufacturer

Pfizer

Sanofi Aventis US

Dosage forms

Tablet

Drug class

Antihistamine

Boxed warning

None

Half-life

about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours)

—

Treats

Anxiety Disorders, Nausea, Pruritus

Headache, Sleep Initiation and Maintenance Disorders, Perennial Allergic Rhinitis

Get decaprynhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is better-rated, Atarax or Decapryn?

By our independent rating, Decapryn scores higher — 3.5 vs 3.2 out of 5 for Atarax. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Atarax and Decapryn?

Atarax contains Hydroxyzine Hydrochloride, while Decapryn contains Doxylamine Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.