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ASTELIN vs PATADAY ONCE DAILY RELIEF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Rating

72/100
New

Pharmacy pays

$0.58 /mL
$1.23 /g

Type

RX
OTC

Active ingredient

AZELASTINE HYDROCHLORIDE
OLOPATADINE HYDROCHLORIDE

Manufacturer

Dosage forms

Spray/Inhaler, metered
Solution

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Treats

Allergic Conjunctivitis, Perennial Allergic Rhinitis, Vasomotor Rhinitis
Allergic Conjunctivitis

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Frequently asked questions

What is the difference between Astelin and Pataday Once Daily Relief?

Astelin contains Azelastine Hydrochloride, while Pataday Once Daily Relief contains Olopatadine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.