ASMANEX TWISTHALER vs CORT-DOME

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ASMANEX TWISTHALER and CORT-DOME are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ASMANEX TWISTHALER	CORT-DOME
Rating	70/100	New
Pharmacy pays	$0.41 /g	$0.15 /g
Type	RX	RX
Active ingredient	MOMETASONE FUROATE	HYDROCORTISONE
Manufacturer	Organon	Bayer Pharms
Dosage forms	Spray/Inhaler	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	about 1.5 hours
Treats	Facial Dermatoses, Foot Dermatoses, Hand Dermatoses	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

asmanex twisthaler cort-dome

Rating

70/100

New

Pharmacy pays

$0.41 /g

$0.15 /g

Type

Active ingredient

MOMETASONE FUROATE

HYDROCORTISONE

Manufacturer

Organon

Bayer Pharms

Dosage forms

Spray/Inhaler

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

about 1.5 hours

Treats

Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

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Frequently asked questions

Which is cheaper, Asmanex Twisthaler or Cort-Dome?

Cort-Dome costs pharmacies less to acquire — about $0.15 vs $0.41 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Asmanex Twisthaler and Cort-Dome?

Asmanex Twisthaler contains Mometasone Furoate, while Cort-Dome contains Hydrocortisone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.