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ASENAPINE MALEATE vs RISPERDAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. ASENAPINE MALEATE and RISPERDAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
70/100

Pharmacy pays

~$73.98 /30
~$2.07 /30

Type

RX
RX

Active ingredient

ASENAPINE MALEATE
RISPERIDONE

Dosage forms

Tablet
Solution, Tablet

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Half-life

about 24 hours (terminal/elimination half-life)
about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)

Treats

Bipolar Disorder, Schizophrenia
Autistic Disorder, Bipolar Disorder, Dementia

Frequently asked questions

Which is better-rated, Asenapine Maleate or Risperdal?

Asenapine Maleate and Risperdal are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Asenapine Maleate or Risperdal?

Risperdal costs pharmacies less to acquire — about $2.07 vs $73.98 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Asenapine Maleate and Risperdal?

Asenapine Maleate contains Asenapine Maleate, while Risperdal contains Risperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.