ASENAPINE MALEATE vs REXULTI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ASENAPINE MALEATE and REXULTI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ASENAPINE MALEATE	REXULTI
Rating	70/100	New
Pharmacy pays	~$73.98 /30	—
Type	RX	RX
Active ingredient	ASENAPINE MALEATE	BREXPIPRAZOLE
Manufacturer	Breckenridge	Otsuka
Dosage forms	Tablet	Tablet, Kit
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	about 24 hours (terminal/elimination half-life)	—
Treats	Bipolar Disorder, Schizophrenia	Major Depressive Disorder, Schizophrenia

asenapine maleate rexulti

Rating

70/100

New

Pharmacy pays

~$73.98 /30

—

Type

Active ingredient

ASENAPINE MALEATE

BREXPIPRAZOLE

Manufacturer

Breckenridge

Otsuka

Dosage forms

Tablet

Tablet, Kit

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

about 24 hours (terminal/elimination half-life)

—

Treats

Bipolar Disorder, Schizophrenia

Major Depressive Disorder, Schizophrenia

Frequently asked questions

What is the difference between Asenapine Maleate and Rexulti?

Asenapine Maleate contains Asenapine Maleate, while Rexulti contains Brexpiprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.