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ASACOL HD vs COLAZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ASACOL HD and COLAZAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

asacol hdcolazal

Rating

72/100
70/100

Pharmacy pays

~$26.72 /30
~$11.17 /30

Type

RX
RX

Active ingredient

MESALAMINE
BALSALAZIDE DISODIUM

Manufacturer

Abbvie
Valeant Pharm Intl

Dosage forms

Tablet, delayed release
Capsule

Drug class

Aminosalicylate
Aminosalicylate

Boxed warning

None
None

Half-life

about 7 to 9 hours (apparent terminal half-life)
—

Treats

Ulcerative Colitis, Proctitis, Sigmoid Diseases
Ulcerative Colitis

Frequently asked questions

Which is better-rated, Asacol Hd or Colazal?

By our independent rating, Asacol Hd scores higher — 3.6 vs 3.5 out of 5 for Colazal. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Asacol Hd or Colazal?

Colazal costs pharmacies less to acquire — about $11.17 vs $26.72 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Asacol Hd and Colazal?

Asacol Hd contains Mesalamine, while Colazal contains Balsalazide Disodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.