ARYNTA vs COTEMPLA XR-ODT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ARYNTA and COTEMPLA XR-ODT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ARYNTA	COTEMPLA XR-ODT
Rating	70/100	New
Pharmacy pays	—	~$18.94 /30
Type	RX	RX
Active ingredient	LISDEXAMFETAMINE DIMESYLATE	METHYLPHENIDATE
Manufacturer	Azurity	Neos Theraps Inc
Dosage forms	Solution	Tablet, orally disintegrating
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	Boxed warning	Boxed warning
Half-life	less than 1 hour (parent drug)	about 2.7 hours
Treats	Attention Deficit Disorder with Hyperactivity, Binge Drinking	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

arynta cotempla xr-odt

Rating

70/100

New

Pharmacy pays

—

~$18.94 /30

Type

Active ingredient

LISDEXAMFETAMINE DIMESYLATE

METHYLPHENIDATE

Manufacturer

Azurity

Neos Theraps Inc

Dosage forms

Solution

Tablet, orally disintegrating

Drug class

Central Nervous System Stimulant

Boxed warning

Half-life

less than 1 hour (parent drug)

about 2.7 hours

Treats

Attention Deficit Disorder with Hyperactivity, Binge Drinking

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Frequently asked questions

What is the difference between Arynta and Cotempla XR-ODT?

Arynta contains Lisdexamfetamine Dimesylate, while Cotempla XR-ODT contains Methylphenidate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.