ARIPIPRAZOLE vs CLOZAPINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. ARIPIPRAZOLE and CLOZAPINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ARIPIPRAZOLE	CLOZAPINE
Rating	66/100	70/100
Pharmacy pays	$0.13 /mL	~$30.62 /30
Type	RX	RX
Active ingredient	ARIPIPRAZOLE	CLOZAPINE
Manufacturer	Apotex	Par Pharm
Dosage forms	Solution, Tablet, Tablet, orally disintegrating	Tablet, Tablet, orally disintegrating
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	None	None
Half-life	about 75 hours (mean elimination half-life of the parent drug in typical adults)	about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)
Treats	Schizophrenia	Bipolar Disorder, Psychotic Disorders, Schizophrenia

aripiprazole clozapine

Rating

66/100

70/100

Pharmacy pays

$0.13 /mL

~$30.62 /30

Type

Active ingredient

ARIPIPRAZOLE

CLOZAPINE

Manufacturer

Apotex

Par Pharm

Dosage forms

Solution, Tablet, Tablet, orally disintegrating

Tablet, Tablet, orally disintegrating

Drug class

Atypical Antipsychotic

Boxed warning

None

Half-life

about 75 hours (mean elimination half-life of the parent drug in typical adults)

about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)

Treats

Schizophrenia

Bipolar Disorder, Psychotic Disorders, Schizophrenia

Frequently asked questions

Which is better-rated, Aripiprazole or Clozapine?

By our independent rating, Clozapine scores higher — 3.5 vs 3.3 out of 5 for Aripiprazole. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Aripiprazole and Clozapine?

Aripiprazole contains Aripiprazole, while Clozapine contains Clozapine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.