ARIMIDEX vs EXEMESTANE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ARIMIDEX and EXEMESTANE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ARIMIDEX	EXEMESTANE
Rating	70/100	72/100
Pharmacy pays	~$4.15 /30	~$18.36 /30
Type	RX	RX
Active ingredient	ANASTROZOLE	EXEMESTANE
Manufacturer	Astrazeneca	Rising
Dosage forms	Tablet	Tablet
Drug class	Aromatase Inhibitor	Aromatase Inhibitor
Boxed warning	None	None
Treats	Breast Neoplasms	Breast Neoplasms

arimidex exemestane

Rating

70/100

72/100

Pharmacy pays

~$4.15 /30

~$18.36 /30

Type

Active ingredient

ANASTROZOLE

EXEMESTANE

Manufacturer

Astrazeneca

Rising

Dosage forms

Tablet

Drug class

Aromatase Inhibitor

Boxed warning

None

Treats

Breast Neoplasms

Frequently asked questions

Which is better-rated, Arimidex or Exemestane?

By our independent rating, Exemestane scores higher — 3.6 vs 3.5 out of 5 for Arimidex. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Arimidex or Exemestane?

Arimidex costs pharmacies less to acquire — about $4.15 vs $18.36 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Arimidex and Exemestane?

Arimidex contains Anastrozole, while Exemestane contains Exemestane — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.