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ARAVA vs CUPRIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. ARAVA and CUPRIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
70/100

Pharmacy pays

~$9.44 /30

Type

RX
RX

Active ingredient

LEFLUNOMIDE
PENICILLAMINE

Dosage forms

Tablet
Capsule

Drug class

Antirheumatic Agent
Antirheumatic Agent

Treats

Rheumatoid Arthritis
Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

Which is better-rated, Arava or Cuprimine?

Arava and Cuprimine are tied at 3.5 out of 5 by our independent rating.

What is the difference between Arava and Cuprimine?

Arava contains Leflunomide, while Cuprimine contains Penicillamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.