APTENSIO XR vs CAFCIT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. APTENSIO XR and CAFCIT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	APTENSIO XR	CAFCIT
Rating	New	72/100
Pharmacy pays	~$18.94 /30	~$2.58 /30
Type	RX	RX
Active ingredient	METHYLPHENIDATE HYDROCHLORIDE	CAFFEINE CITRATE
Manufacturer	Rhodes Pharms	Hikma
Dosage forms	Capsule, extended release	Injectable
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	Boxed warning	None
Half-life	about 2.7 hours	—
Treats	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy	Apnea, Fatigue

aptensio xr cafcit

Rating

New

72/100

Pharmacy pays

~$18.94 /30

~$2.58 /30

Type

Active ingredient

METHYLPHENIDATE HYDROCHLORIDE

CAFFEINE CITRATE

Manufacturer

Rhodes Pharms

Hikma

Dosage forms

Capsule, extended release

Injectable

Drug class

Central Nervous System Stimulant

Boxed warning

None

Half-life

about 2.7 hours

—

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Apnea, Fatigue

Frequently asked questions

Which is cheaper, Aptensio XR or Cafcit?

Cafcit costs pharmacies less to acquire — about $2.58 vs $18.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Aptensio XR and Cafcit?

Aptensio XR contains Methylphenidate Hydrochloride, while Cafcit contains Caffeine Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.