Skip to content
ppharmaranks
Menu

APREMILAST vs OTEZLA XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

70/100
72/100

Pharmacy pays

Type

RX
RX

Active ingredient

APREMILAST
APREMILAST

Dosage forms

Tablet
Tablet, extended release

Drug class

Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 Inhibitor

Boxed warning

None
None

Half-life

about 6 to 9 hours (terminal elimination half-life)
about 6 to 9 hours (terminal elimination half-life)

Treats

Psoriatic Arthritis
Psoriatic Arthritis

Frequently asked questions

Which is better-rated, Apremilast or Otezla XR?

By our independent rating, Otezla XR scores higher — 3.6 vs 3.5 out of 5 for Apremilast. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Apremilast and Otezla XR?

Both Apremilast and Otezla XR share the active ingredient Apremilast.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.