ANAFRANIL vs JANIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. ANAFRANIL and JANIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ANAFRANIL	JANIMINE
Rating	70/100	70/100
Pharmacy pays	~$7.16 /30	~$2.54 /30
Type	RX	RX
Active ingredient	CLOMIPRAMINE HYDROCHLORIDE	IMIPRAMINE HYDROCHLORIDE
Manufacturer	Specgx LLC	Abbott
Dosage forms	Capsule	Tablet
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	Boxed warning	None
Treats	Depressive Disorder, Obsessive-Compulsive Disorder, Pain	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

anafranil janimine

Rating

70/100

Pharmacy pays

~$7.16 /30

~$2.54 /30

Type

Active ingredient

CLOMIPRAMINE HYDROCHLORIDE

IMIPRAMINE HYDROCHLORIDE

Manufacturer

Specgx LLC

Abbott

Dosage forms

Capsule

Tablet

Drug class

Tricyclic Antidepressant

Boxed warning

None

Treats

Depressive Disorder, Obsessive-Compulsive Disorder, Pain

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

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Frequently asked questions

Which is better-rated, Anafranil or Janimine?

Anafranil and Janimine are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Anafranil or Janimine?

Janimine costs pharmacies less to acquire — about $2.54 vs $7.16 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Anafranil and Janimine?

Anafranil contains Clomipramine Hydrochloride, while Janimine contains Imipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.