AMRIX vs PARAFLEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. AMRIX and PARAFLEX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMRIX	PARAFLEX
Rating	56/100	New
Pharmacy pays	~$0.63 /30	~$16.14 /30
Type	RX	RX
Active ingredient	CYCLOBENZAPRINE HYDROCHLORIDE	CHLORZOXAZONE
Manufacturer	Teva	Ortho Mcneil Pharm
Dosage forms	Capsule, extended release	Tablet
Drug class	Muscle Relaxant	Muscle Relaxant
Boxed warning	None	None
Half-life	about 18 hours (range roughly 8 to 37 hours) for the standard immediate-release tablet in typical adults	—
Treats	Muscle Cramp, Muscle Rigidity, Muscle Spasticity	Muscle Cramp, Muscle Rigidity, Myositis

amrix paraflex

Rating

56/100

New

Pharmacy pays

~$0.63 /30

~$16.14 /30

Type

Active ingredient

CYCLOBENZAPRINE HYDROCHLORIDE

CHLORZOXAZONE

Manufacturer

Teva

Ortho Mcneil Pharm

Dosage forms

Capsule, extended release

Tablet

Drug class

Muscle Relaxant

Boxed warning

None

Half-life

about 18 hours (range roughly 8 to 37 hours) for the standard immediate-release tablet in typical adults

—

Treats

Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Muscle Cramp, Muscle Rigidity, Myositis

Frequently asked questions

Which is cheaper, Amrix or Paraflex?

Amrix costs pharmacies less to acquire — about $0.63 vs $16.14 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Amrix and Paraflex?

Amrix contains Cyclobenzaprine Hydrochloride, while Paraflex contains Chlorzoxazone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.