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AMOXICILLIN vs POLYCILLIN-N

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. AMOXICILLIN and POLYCILLIN-N are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
New

Pharmacy pays

$0.05 /mL
~$13.42 /30

Type

RX
RX

Active ingredient

AMOXICILLIN
AMPICILLIN SODIUM

Dosage forms

Capsule, Powder, Tablet, chewable, Tablet
Injectable

Drug class

Penicillin-Class Antibacterial
Penicillin-Class Antibacterial

Boxed warning

None
None

Half-life

about 1 hour (roughly 61 minutes)

Treats

Actinomycosis, Human Bites, Chlamydia Infections
Actinomycosis, Human Bites, Bacillary Dysentery

Frequently asked questions

What is the difference between Amoxicillin and Polycillin-N?

Amoxicillin contains Amoxicillin, while Polycillin-N contains Ampicillin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.