AMITRIPTYLINE HYDROCHLORIDE vs PAMELOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. AMITRIPTYLINE HYDROCHLORIDE and PAMELOR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMITRIPTYLINE HYDROCHLORIDE	PAMELOR
Rating	68/100	70/100
Pharmacy pays	~$2.72 /30	$0.17 /mL
Type	RX	RX
Active ingredient	AMITRIPTYLINE HYDROCHLORIDE	NORTRIPTYLINE HYDROCHLORIDE
Manufacturer	Sandoz	Specgx LLC
Dosage forms	Tablet	Capsule
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	Boxed warning	None
Treats	Depressive Disorder, Pain	Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

amitriptyline hydrochloride pamelor

Rating

68/100

70/100

Pharmacy pays

~$2.72 /30

$0.17 /mL

Type

Active ingredient

AMITRIPTYLINE HYDROCHLORIDE

NORTRIPTYLINE HYDROCHLORIDE

Manufacturer

Sandoz

Specgx LLC

Dosage forms

Tablet

Capsule

Drug class

Tricyclic Antidepressant

Boxed warning

None

Treats

Depressive Disorder, Pain

Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

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Frequently asked questions

Which is better-rated, Amitriptyline Hydrochloride or Pamelor?

By our independent rating, Pamelor scores higher — 3.5 vs 3.4 out of 5 for Amitriptyline Hydrochloride. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Amitriptyline Hydrochloride and Pamelor?

Amitriptyline Hydrochloride contains Amitriptyline Hydrochloride, while Pamelor contains Nortriptyline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.