AMITIZA vs ZELNORM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. AMITIZA and ZELNORM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMITIZA	ZELNORM
Rating	New	New
Pharmacy pays	~$20.52 /30	—
Type	RX	RX
Active ingredient	LUBIPROSTONE	TEGASEROD MALEATE
Manufacturer	Sucampo Pharma LLC	Alfasigma
Dosage forms	Capsule	Tablet
Drug class	Chloride Channel Activator	—
Boxed warning	None	None
Treats	Constipation, Irritable Bowel Syndrome	Constipation, Irritable Bowel Syndrome

amitiza zelnorm

Rating

New

Pharmacy pays

~$20.52 /30

—

Type

Active ingredient

LUBIPROSTONE

TEGASEROD MALEATE

Manufacturer

Sucampo Pharma LLC

Alfasigma

Dosage forms

Capsule

Tablet

Drug class

Chloride Channel Activator

—

Boxed warning

None

Treats

Constipation, Irritable Bowel Syndrome

Frequently asked questions

What is the difference between Amitiza and Zelnorm?

Amitiza contains Lubiprostone, while Zelnorm contains Tegaserod Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.