AMIODARONE HYDROCHLORIDE vs BETAPACE AF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. AMIODARONE HYDROCHLORIDE and BETAPACE AF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMIODARONE HYDROCHLORIDE	BETAPACE AF
Rating	68/100	New
Pharmacy pays	~$3.68 /30	~$2.96 /30
Type	RX	RX
Active ingredient	AMIODARONE HYDROCHLORIDE	SOTALOL HYDROCHLORIDE
Manufacturer	Fresenius Kabi USA	Legacy Pharma
Dosage forms	Injectable, Tablet	Tablet
Drug class	Antiarrhythmic	Antiarrhythmic
Boxed warning	None	Boxed warning
Half-life	—	about 12 hours (the label gives a mean elimination half-life of 12 hours)
Treats	Supraventricular Tachycardia, Ventricular Fibrillation	Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia

amiodarone hydrochloride betapace af

Rating

68/100

New

Pharmacy pays

~$3.68 /30

~$2.96 /30

Type

Active ingredient

AMIODARONE HYDROCHLORIDE

SOTALOL HYDROCHLORIDE

Manufacturer

Fresenius Kabi USA

Legacy Pharma

Dosage forms

Injectable, Tablet

Tablet

Drug class

Antiarrhythmic

Boxed warning

None

Boxed warning

Half-life

—

about 12 hours (the label gives a mean elimination half-life of 12 hours)

Treats

Supraventricular Tachycardia, Ventricular Fibrillation

Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia

Frequently asked questions

Which is cheaper, Amiodarone Hydrochloride or Betapace Af?

Betapace Af costs pharmacies less to acquire — about $2.96 vs $3.68 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Amiodarone Hydrochloride and Betapace Af?

Amiodarone Hydrochloride contains Amiodarone Hydrochloride, while Betapace Af contains Sotalol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.