AMBRISENTAN vs LETAIRIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	AMBRISENTAN	LETAIRIS
Rating	66/100	70/100
Pharmacy pays	~$255.61 /30	~$255.61 /30
Type	RX	RX
Active ingredient	AMBRISENTAN	AMBRISENTAN
Manufacturer	Zydus Pharms USA Inc	Gilead Sciences Inc
Dosage forms	Tablet	Tablet
Drug class	Endothelin Receptor Antagonist	Endothelin Receptor Antagonist
Boxed warning	Boxed warning	Boxed warning
Treats	Pulmonary Hypertension	Pulmonary Hypertension

ambrisentan letairis

Rating

66/100

70/100

Pharmacy pays

~$255.61 /30

Type

Active ingredient

AMBRISENTAN

Manufacturer

Zydus Pharms USA Inc

Gilead Sciences Inc

Dosage forms

Tablet

Drug class

Endothelin Receptor Antagonist

Boxed warning

Treats

Pulmonary Hypertension

Frequently asked questions

Which is better-rated, Ambrisentan or Letairis?

By our independent rating, Letairis scores higher — 3.5 vs 3.3 out of 5 for Ambrisentan. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Ambrisentan or Letairis?

Pharmacies pay about the same to acquire either one — roughly $255.61 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Ambrisentan and Letairis?

Both Ambrisentan and Letairis share the active ingredient Ambrisentan.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.