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AMBIEN vs AMBIEN CR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Rating

70/100
70/100

Pharmacy pays

~$1.04 /30
~$1.04 /30

Type

RX
RX

Active ingredient

ZOLPIDEM TARTRATE
ZOLPIDEM TARTRATE

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

Gamma-Aminobutyric Acid A Receptor Positive Modulator
Gamma-Aminobutyric Acid A Receptor Positive Modulator

Half-life

about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults
about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults

Treats

Sleep Initiation and Maintenance Disorders
Sleep Initiation and Maintenance Disorders

Frequently asked questions

Which is better-rated, Ambien or Ambien CR?

Ambien and Ambien CR are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Ambien or Ambien CR?

Pharmacies pay about the same to acquire either one — roughly $1.04 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Ambien and Ambien CR?

Both Ambien and Ambien CR share the active ingredient Zolpidem Tartrate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.