AMBIEN CR vs LARGON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. AMBIEN CR and LARGON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	AMBIEN CR	LARGON
Rating	70/100	72/100
Pharmacy pays	~$1.04 /30	—
Type	RX	RX
Active ingredient	ZOLPIDEM TARTRATE	PROPIOMAZINE HYDROCHLORIDE
Manufacturer	Cosette	Hikma
Dosage forms	Tablet	Injectable
Drug class	Gamma-Aminobutyric Acid A Receptor Positive Modulator	—
Boxed warning	Boxed warning	None
Half-life	about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults	—
Treats	Sleep Initiation and Maintenance Disorders	Anxiety Disorders, Sleep Initiation and Maintenance Disorders

ambien cr largon

Rating

70/100

72/100

Pharmacy pays

~$1.04 /30

—

Type

Active ingredient

ZOLPIDEM TARTRATE

PROPIOMAZINE HYDROCHLORIDE

Manufacturer

Cosette

Hikma

Dosage forms

Tablet

Injectable

Drug class

Gamma-Aminobutyric Acid A Receptor Positive Modulator

—

Boxed warning

None

Half-life

about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults

—

Treats

Sleep Initiation and Maintenance Disorders

Anxiety Disorders, Sleep Initiation and Maintenance Disorders

Frequently asked questions

Which is better-rated, Ambien CR or Largon?

By our independent rating, Largon scores higher — 3.6 vs 3.5 out of 5 for Ambien CR. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Ambien CR and Largon?

Ambien CR contains Zolpidem Tartrate, while Largon contains Propiomazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.